Bynum had to be helped off the court with 6:55 to go in the first quarter and scored seven points in five minutes of action before exiting.
"I didn't hear any pops, basically I just hurt the knee, the inside of my leg," Bynum said.
X-rays were negative. He is expected to undergo further testing Sunday morning.
Entering the game averaging 14.2 points and 8.4 rebounds this season, Bynum has become a force as of late, scoring 27 points in Friday's win over Minnesota as part of five straight double-doubles. The 7-footer was forced to miss the entire second half of last season and the playoffs after suffering a partially dislocated kneecap last January -- also against Memphis.