Chargers quarterback Philip Rivers was 24 of 32 for 284 yards and Malcom Floyd had six catches for 109 yards.
But the name of the game was Dante Rosario. In for the injured Antonio Gates, Rosario scored three of the Chargers five touchdowns.
Gates plays such a large role in the team's offense that if he doesn't play, Rosario said the entire team needs to step it up. After the game, Rosario said it felt good to contribute.
He said head coach Norv Turner told the team to stay focused on one game at a time but that the players are showing spurts that this season could be a very good one for the franchise.
"When we function in a normal level or operate in a way we'd like to, you can see we have a chance to be real good. We still have some rough spots with a lot of work to do and continue to get better," head coach Norv Turner told the media after the game.
He gave the offensive line and defensive line game balls to congratulate them for a game well played.
"We're a lot more athletic, we're a lot more physical, we're a lot faster group than we've been and that's exciting," Turner said.
Before the game, the San Diego Chargers officialy retired #55 in honor of the late Hall of Fame linebacker Junior Seau.
Chargers’ legendary quarterback Dan Fouts officiated the ceremony and handed the jersey to Seau's four children.
“There is no one more deserving than our friend Junior,” Fouts said.
Fouts' #14 and Lance Alworth's # 19 are the only other retired Chargers numbers.
Fans enjoyed an unusual Chargers team dressed all in white. The team wore white pants and white jerseys together for the first time since the new uniforms were introduced in 2007.
"It was awesome, it was great," said Chargers safety Eric Weddle after the game. " We've been lobbying for all whites since I've been here. It was a great switchup."
Weddle added that even though the home opener energy was great, the team needs to get back to business and turn their focus to Atlanta.