A woman faces felony DUI charges for driving the wrong-way on the San Diego-Coronado Bridge and colliding head-on with another vehicle.
The California Highway Patrol reported a westbound vehicle was involved in a head-on collision just 300 yards east of the toll plaza at 4:18 a.m.
A white sedan was driving the wrong way across the bridge, officials said.
CHP Officer Jake Sanchez said the driver of a Ford Fusion, Briana Rall, 24, was spotted by a patrol officer at the toll plaza.
By the time the CHP officer caught up with Rall, the crash had occurred.
Rall, who suffered moderate injuries in the crash, will be charged with felony DUI, Sanchez said.
The driver of an F-150 was struck head-on by Rall's vehicle. The 49-year-old woman was taken to UCSD Medical Center with major injuries, the CHP official said.
The driver of a third vehicle, a Dodge Ram pickup, was struck by the F-150. The 27-year-old man suffered moderate injuries and was also being treated at UCSD.
Traffic in both directions was immediately stopped and held for several hours while CHP and Coronado police investigated.