Ultimately, Kathy Griffin and "Fashion Police" were not the right fit.
The comedian is leaving the E! show after seven episodes as host, the network confirmed in a statement Thursday.
"We can confirm that Kathy Griffin is leaving E!'s 'Fashion Police'," the statement said. "We wish her all the best and are grateful for her time on the show, as well as the many laughs that she gave us all. Fashion Police will return, as scheduled, on Monday, March 30, at 9 p.m. with our talented co-hosts Giuliana Rancic and Brad Goreski, and executive producer Melissa Rivers."
Griffin, who replaced the late Joan Rivers on the series, made the announcement via a lengthy Twitter statement Thursday.
"I thought that I could bring my brand of humor to Fashion Police so that beautiful people in beautiful dresses could be teased when appropriate," Griffin wrote. "My brand of humor, while unrepentant and unafraid, is all about CONTEXT. There is plenty to make fun of in pop culture without bringing people's bodies into it."
"I wish E! and the E! team only the best and I hope to continue to make you all laugh performing live or on television where I can be smart, irreverent, unrepentant and unafraid in an observational way that is candid, honest and justified," the statement added. "Thank you to my fans for taking this ride with me."
Griffin’s announcement comes just weeks after co-host Kelly Osbourne stepped down from the show following the controversy surrounding panelist Giuliana Rancic’s remarks about Disney star Zendaya’s Oscars hairstyle.