The Chargers will not have safety Jahleel Addae or cornerback Chris Davis for Sunday's home opener against the Seahawks. Both have been ruled out with leg injuries. Neither was available on Monday night against the Cardinals, either.
However, two other defensive starters may be on the sidelines, as well. Linebacker Melvin Ingram has a hamstring injury. He only practiced part-time and is questionable (50-50) to play. Cornerback Brandon Flowers, who played extremely well in his San Diego debut Monday, injured his groin during practice this week and is also questionable.
Facing the defending Super Bowl champions and a quarterback like Russell Wilson, who is able to utilize a multitude of targets in the passing game, the Chargers would be at quite the disadvantage not having a 2-time Pro Bowler like Flowers on the field.
If neither Ingram nor Flowers can go, veteran Dwight Freeney and rookie Jason Verrett are the likely candidates to step in to the starting rotation.
Everybody else on the Chargers roster is expected to play.
As for the Seahawks, they'll be without running back Christine Michael, Linebacker Kevin Pierre-Louis and cornerback Tharold Smith. Tight end Cooper Heifet is doubtful with a knee injury. None of those players would impact Seattle as much as losing Ingram or Flowers would hinder San Diego.