coronavirus April 6, 2021 10:44 am Moderna COVID-19 Vaccine Lasts at Least 6 Months The Moderna vaccine offers protection against COVID-19 for at least six months, according to a report in the New England Journal of Medicine. US & World Videos 2:33 CDPH releases updated Covid-19 isolation guidelines 1:31 CDC recommends updated Covid shot for everyone ages 6 months and up 2:17 San Diego and California's COVID-19 Emergency Declarations Are Expiring. Here's What That Means 2:30 San Diego and California COVID-19 Emergency Declarations Expire Tuesday 3:26 COVID, Flu Cases Down Slightly; Doctors Urge Caution