The Padres apparently are not very good at making first impressions.
San Diego suffered a 4-2 defeat Thursday evening in Atlanta, falling to just 5-18 in series openers this season.
Tyson Ross pitched six innings and gave up only three hits and three runs.
Ender Inciarte provided a boost for the Braves when he homered with nobody on base in the third inning to make it 2-0 Atlanta.
Inciarte later knocked in another run on an RBI groundout.
But Anibal Sanchez was even better for the Braves.
Sanchez earned his first career victory against the Padres in six tries after tossing seven shutout innings and not walking a single batter.
The righty eventually left with six strikeouts and only four hits allowed.
Eric Hosmer got the Padres on the board with a two-run double in the top of the eighth against reliever Dan Winkler.
Jose Pirela, Franmil Reyes and A.J. Ellis each added two hits apiece.
Andy Green’s club has shown the ability to bounce back after the majority of its series-opening losses.
The Padres are 28-20 in all other games this season.
Their next chance to get back on track comes Friday night when Clayton Richard opposes Julio Teheran in the second matchup this week between the two teams.