Two big rigs and a tour bus were involved in a crash in Hacienda Heights Wednesday morning, injuring 23 people.
A Los Angeles County Fire Department spokesman said 23 people are being treated for minor to moderate injuries.
Thirteen were taken to local hospitals.
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CHP Officer Al Perez said the incident preliminarily appeared to have begun with the big rigs.
"One of the big rigs struck another big rig and in turn that impact caused that second big rig to go toward the center median and in turn impact with the charter bus that was traveling either in the carpool lane or the number one lane," he said.
Investigators were not able to immediately speak with the bus driver because he was hospitalized with moderate injuries.
Passengers on the Pala Casino-bound BusLimo Express vehicle were seen walking on the freeway following the crash.
Thirty people were on the bus, which was making a day trip from Monterey Park to the casino south of Temecula.
The crash was reported just before 10 a.m. on the eastbound 60 Freeway at Seventh Avenue, according to the LA County Fire Department.
Authorities shut down all but one lane on the eastbound side of the freeway. The lanes were all reopened just before 1 p.m.
Traffic was backed up for miles.
The cause of the initial crash between the trucks was under investigation.
The bus company sent a second bus to pick up passengers who were not hurt and took them to the casino.