The Powerball jackpot has risen to $334 million, the 12th largest in the game's history.
The next drawing is set for Saturday and the lump-sum cash prize for the winner is $205 million.
There were no tickets sold with all six numbers in the most recent drawing of the multi-state lottery game.
U.S. & World
A ticket with five numbers in Wednesday's drawing, but missing the Powerball number, was sold in San Jose and is worth $1,900,176. Another ticket with five numbers, but missing the Powerball number, was sold in Pennsylvania and is worth $1 million, the Multi-State Lottery Association, which conducts the game, announced. California law requires major payoffs of lottery games to be paid on a pari-mutuel basis.
The numbers drawn Wednesday night were 12, 36, 38, 54, 61 and the Powerball number was 22. The estimated jackpot was $300 million. The drawing was the 16th since the last time a ticket with all six numbers was sold.
Iowa Lottery spokesman Kevin Kirkpatrick says the last time the prize was close to this amount was in March 2013, when a New Jersey man won $338 million. Powerball's largest jackpot was more than $590 million in May 2013.
Kirkpatrick says the game would have to continue a few more rounds without a winner before it could reach that level.
The odds of winning the Powerball jackpot is 1 in about 293 million, according to the Powerball website. The overall chance of winning a prize is 1 in 24.87.
The Powerball game is played in 44 states, the District of Columbia, Puerto Rico and U.S. Virgin Islands. Drawing entries close at 7 p.m. in California.
City News Serivice and the Associated Press contributed to this report.