All but one westbound lane of State Route 52 in University City were shut down as firefighters extricated multiple passengers in a three-car crash.
As of 7 p.m., all lanes have been reopened.
A Sig Alert was issued at 5:53 p.m. for SR-52 near westbound Interstate 805 after at least four passengers became trapped in the wreck.
At least two passengers were reported in critical condition, according to the San Diego Fire-Rescue Department (SDFD).
No other information was available.
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