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A woman was under arrest Friday, accused of murder for striking and running over a motorcyclist on a busy San Diego highway at rush hour.

Imperial Beach resident Darla Renee Jackson, 26, was driving a black Nissan Altima northbound on Interstate 5 near E Street in Chula Vista at around 5:30 p.m. Thursday.

California Highway Patrol (CHP) officers said Jackson and a man on a red Ducati motorcycle got into some type of disagreement on the roadway.

After the two drivers transitioned from I-5 to eastbound State Route 54 and passed National City Boulevard, Jackson hit the Ducati from behind and ran over the rider, CHP officers said.

The motorcyclist — identified by friends as 39-year-old Zachary Buob — died about an hour later at a hospital. A Santee resident, Buob was an active duty Chief Petty Officer in the Navy's special operations.

Jackson was arrested and now faces one count of murder in what officers are calling a road rage incident. She was booked into Las Colinas Detention and Re-entry Facility and is scheduled to appear in court Tuesday.

The crash caused a Sig Alert for more than two-and-a-half along SR-54 in the middle of a very busy evening commute. Investigators are in the process of tracking down drivers who may have witnessed the act of road rage from start to finish.

Anyone who may have seen anything involving these two vehicles should contact the CHP investigator at (619) 220-5492.

Describing the victim, friend Kathryn Cramer said Buob served in the military for more than 20 years and completed many tours overseas.

"He was so strong but his heart was so sweet," she said in an email. "He was truly one of the 'good guys' and my heart is broken. My prayers are with his Mom and Dad and family. He loved them so much."

Another good friend, Tim James, told NBC 7 Buob worked as an elite special boat operator, but motorcycles and trucks were his passion — only overshadowed by his love for family and friends.

"Zach was energetic, intelligent and a superb leader. He would light up any room he entered with his friendliness and wittiness...a heart of gold," said James in an email.

CHP Officer Jake Sanchez warned drivers Friday to not let road rage ever escalate to such a deadly point. He warned drivers not to pick fights with others on the roadway because you don't know what that person may be going through or if that person could be capable of something like this.

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A fire broke out in the area of Geary Blvd and Parker Avenue on Wednesday, Feb. 6, 2019, in San Francisco.
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According to the fire department, a third party crew was digging in front of Hong Kong Loung II when they hit a gas line, causing an explosion.
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PG&E spokesperson Paul Doherty speaks to reporters at the scene. He says crews are working closing with firefighters.
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An aerial view shows towering flames as crews battle the San Francisco fire.
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An aerial view shows towering flames as crews battle the San Francisco fire.
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An aerial view shows towering flames as crews battle the San Francisco fire.
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Mayor London Breed said San Francisco firefighters, police and the Dept. of Emergency Management are on the scene.
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Aerial view of the aftermath of a fire sparked by a gas line explosion in San Francisco. (Feb. 6, 2019)
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