A woman died Wednesday in a fiery crash involving at least four cars on northbound Interstate 5 approaching Via de la Valle.
The California Highway Patrol issued a SigAlert for traffic heading northbound around 5 a.m.
All northbound lanes were blocked except the carpool lane for hours. The lanes were cleared of the wreckage and reopened just before 8 a.m.
CHP officers say a woman driving a Nissan Sentra was stopped in the fast lane when a silver Honda Accord crashed into the Sentra, killing her.
The man driving the Accord suffered minor to moderate injuries, officers said.
A white Honda Accord appeared to side swipe the silver Accord.
San Diego Fire-Rescue officials identified the driver killed as an 85-year-old La Mesa woman. No details were given on why the Sentra was stopped on I-5 before the crash.