The California Highway Patrol issued a Sig Alert after a serious accident in Chollas View on Christmas Eve.
The crash happened just before 8 p.m. Wednesday on the southbound Interstate 805 transition to eastbound State Route 94.
According to CHP, a car crashed into another car that had stopped in the middle of the freeway. Major injuries have been reported.
The accident brought traffic to a virtual standstill in the area. CHP officers were on scene directing traffic.