New Mexico was red hot, especially in the second half when the Lobos shot 60% from the floor.
The Aztecs had a miserable night from beyond the arc, hitting on only 4 of 23 attempts. Their overall shooting percentage was just 36% for the game.
New Mexico's big men combined for 41 points. Alex Kirk, the 7 footer was 3-for-3 on three pointers.
Australian forward Cameron Bairstow added 16. Kendall Williams, who had 46-points Saturday at Colorado State was held to just eight.
Jamaal Franklin led San Diego State with 16-points.
After losing to New Mexico, the Aztecs cannot win the Mountain West regular season title. They are now three and a half games behind the Lobos with two to play. State closes out the season with a home game against Air Force on Wednesday then on the road Saturday at Boise State.