Zika Vaccines Work in Monkeys, Boosting Hopes for People - NBC 7 San Diego
Zika Virus Outbreak

Zika Virus Outbreak

Coverage of the spread of the Zika virus in the Americas

Zika Vaccines Work in Monkeys, Boosting Hopes for People

The experiment involved a traditional vaccine and two more cutting-edge ones

    processing...

    NEWSLETTERS

    Zika Vaccines Work in Monkeys, Boosting Hopes for People
    AP
    In this Feb. 11, 2016, file photo of aedes aegypti mosquitoes are seen in a mosquito cage at a laboratory in Cucuta, Colombia.

    Three experimental Zika vaccines protected monkeys against infection from the virus, an encouraging sign as research moves into studies in people.

    The success in monkeys, which involved a traditional vaccine and two more cutting-edge ones, "brings us one step closer to a safe and effective Zika vaccine," said Dr. Dan Barouch of Beth Israel Deaconess Medical Center in Boston. "But of course, there's a lot more work to do."

    Barouch and others reported the results in a paper released Thursday by the journal Science. One of the vaccines is expected to enter preliminary human studies this year.

    At least two other vaccines have reached that point already. Inovio Pharmaceuticals announced last week that it had injected its first participant. The National Institute of Allergy and Infectious Diseases gave its first vaccine Tuesday. Both studies focus on assessing vaccine safety.

    Raqqa's Devastation Shows Entire Neighborhoods Destroyed

    [NATL] Raqqa's Devastation Shows Entire Neighborhoods Destroyed

    Shells of buildings, concrete slabs littering dust-choked streets and destroyed cars are all that is left of whole neighborhoods in Raqqa, Syria, after weeks of fighting and bombings between Islamic State militants and the Kurdish-led Syrian Democratic Forces, backed by the U.S.

    (Published Friday, Oct. 20, 2017)

    Efforts to develop a vaccine began after a massive Zika outbreak last year in Brazil, which showed that infection of pregnant women can harm fetal brain development.

    In the monkey study, one vaccine followed the traditional approach, using a dead Zika virus to train the body for fighting off infection. It was injected into eight rhesus monkeys and followed by a booster shot a month later. A month after the booster, the monkeys got a dose of Zika virus.

    None showed any sign of the virus in their blood for the week they were followed. In contrast, eight other monkeys that had gotten a sham vaccine became infected.

    That vaccine, developed at the Walter Reade Army Institute of Research in Silver Spring, Maryland, is expected to begin human testing in October.

    The other two vaccines, produced at Beth Israel and not yet scheduled for human studies, delivered only the DNA of a single virus gene. That spurred the monkeys' bodies to pump out a protein found in the Zika virus, which in turn gave their immune systems to attack on the full virus.

    The two vaccines completely protected a total of eight monkeys against infection.

    Patriots Owner Robert Kraft Teams Up With Nike for Charity

    [NATL] Just for Kicks: Patriots Owner Robert Kraft Teams Up With Nike for Charity

    New England Patriots owner Robert Kraft has teamed up with Nike to celebrate the Pats Super Bowl LI victory over the Atlanta Falcons. The Nike RKK Air Force 1 Flyknit is the fourth collaboration between Kraft and the sneaker company.

    (Published Thursday, Oct. 19, 2017)

    The results "add some encouragement that this might work in humans," said Dr. Anthony Fauci, director of the federal infectious disease institute, who was not involved in the study. The total protection is "good news," he said.

    Experts said it's impossible to know when a Zika vaccine will be approved for use.

    "It's not going to be this year, for sure," Barouch said.

    Child Porn Search Warrant Leads to Massive Weapons Bust

    [NATL] Child Porn Search Warrant Leads to Massive Weapons Bust

    A man in Florida was arrested Thursday for possessing destructive devices in his home.

    Pinellas County sheriff's deputies were serving a search warrant regarding child pornography in the home of Randall Drake when they found the devices and made the arrest.

    Deputies also found maps and aerial photos of Essrig Elementary School, Ben Hill Middle School and a water treatment plant in Hillsborough County.

    (Published Friday, Oct. 20, 2017)

    Fauci said it might be early 2018 if not later.