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Joseph McStay, a Fallbrook businessman; his wife, Summer; and their two children, Gianni 4, Joseph Jr. 3 -- were last seen Feb.4.
In May, investigators from Baja California's state police searched for the McStays in El Rosario in central Baja, after receiving a tip the family was spotted there in late February.
Detectives said there is no evidence the family had financial problems or were facing threats. Since their disappearance, investigators said, the McStays haven't used their bank accounts, credit cards or cell phones.
Anyone with information about the whereabouts of the McStay family is urged to call the San Diego Sheriff's Department at (858) 974-2321 or (858) 565-5200 after-hours.
Tips can also be called in anonymously to CrimeStoppers at 888-580-TIPS(8477). A reward of up to $1,000 is being offered by CrimeStoppers for information leading to an arrest.