The numbers in the Friday night multi-state Mega Millions draw were 14, 19, 21, 42, 45 and the Mega number was 6.
The estimated jackpot was $151 million.
The drawing was the 11th since the last time a ticket with all six numbers were sold.
The odds of matching all five numbers and the Mega number was 1 in 175,711,536, according to the Mega Millions website.
The Mega Millions game was played in 41 states and the District of Columbia.